I was recently contacted by a client to evaluate their Magento store. I realized that the store (even though running in production) had developer mode enabled in their index.php
file:
if (isset($_SERVER['MAGE_IS_DEVELOPER_MODE'])) { //the variable is set.
Mage::setIsDeveloperMode(true);
}
They've been running this store in production for over 2 years. I restored the earliest revision of the file which was from 2013-02-09 and it still had developer mode set to true.
After reading this article by Alan Storm: PHP Error Handling and Magento Developer Mode I can't really think of a reason to recommend that the client disabled developer mode.
Are there any detrimental aspects of having it enabled in production?
Alan Storm's wrap-up:
Developer Mode will help you write cleaner code without subjecting your users to awkward PHP errors when something goes wrong
Seems pretty positive for me. As a rule of thumb, I previously just didn't subject production environment to developer mode.