There's a couple of Modules that are packaged with Magento Open Source these days that promote Magento Partners. I know that disabling
Magento_Signifyd can be done safely without any collateral.
Dotdigitalgroup_Email be disabled safely without interfering with anything?
EDIT: 2.3.4. adds
Dotdigitalgroup_Chat. So, both
Dotdigitalgroup modules need to be either enabled or disabled in pairs. Otherwise this results in an Exception error when attempting to access the backend.
I've included a source to an article I maintain, in case I forgot to make further edits here in the future.