I have Magento Enterprise Edition 18.104.22.168 installed. So do i need to apply security patch SUPEE-10570? Is it compatible with Magento Enterprise Edition 22.214.171.124?
According to their security patch notes here you need to apply that patch. I'll just rewrite only the important parts:
Patches and upgrades are available for the following Magento versions:
Magento Commerce 126.96.36.199-188.8.131.52: SUPEE-10570 or upgrade to Magento Commerce 184.108.40.206
Magento Open Source 220.127.116.11-18.104.22.168: SUPEE-10570 or upgrade to Magento Open Source 22.214.171.124
It also says that the security flaw affects
Magento Commerce prior to 126.96.36.199 which means it affects version
Magento Commerce is
Magento Open Source is
Magento Community Edition.